2,2-bis(4-fluorophenyl)acetic acid - Names and Identifiers
2,2-bis(4-fluorophenyl)acetic acid - Physico-chemical Properties
Molecular Formula | C14H10F2O2
|
Molar Mass | 248.23 |
Density | 1.312±0.06 g/cm3(Predicted) |
Melting Point | 138 °C |
Boling Point | 347.1±32.0 °C(Predicted) |
Flash Point | 163.713°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 4.75±0.10(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.567 |
2,2-bis(4-fluorophenyl)acetic acid - Introduction
Bis(4-fluorophenyl) acetic acid is an organic compound with the chemical formula C14H10F2O2. The following is a description of the nature, use, preparation and safety information of Bis(4-fluorophenyl) acetic acid:
Nature:
-Appearance: White crystalline solid
-Melting point: 121-124 degrees Celsius
-Boiling point: 390-392 degrees Celsius
-Solubility: Soluble in chloroform, dichloromethane and alcohol solvents, slightly soluble in water
Use:
- Bis(4-fluorophenyl) acetic acid can be used as an intermediate in organic synthesis. It can be used to synthesize pesticides, drugs, dyes and anti-cancer drugs.
-In the field of medicine, Bis(4-fluorophenyl) acetic acid is also used to synthesize specific types of non-steroidal anti-inflammatory drugs.
Preparation Method:
- Bis(4-fluorophenyl) acetic acid is usually prepared by fluorination of benzoic acid. First, benzoic acid reacts with anhydrous hydrogen fluoride to form the corresponding aromatic fluoride. Then, it was esterified with acetic acid to obtain Bis(4-fluorophenyl) acetic acid.
Safety Information:
- Bis(4-fluorophenyl) acetic acid has low toxicity, but it is still necessary to pay attention to safe operation and avoid contact with skin and eyes. Wear appropriate personal protective equipment, such as gloves and safety glasses.
-During use or storage, avoid contact with oxidants, strong acids and strong bases to prevent dangerous reactions.
-If the substance is inhaled or ingested, seek medical attention immediately and bring the packaging or label to your doctor's information.
Last Update:2024-04-09 21:01:54